Work

Intramyofiber invasion in a case of oral squamous cell carcinoma; an unusual pattern of skeletal muscle infiltration

Year: 2025

Type: article

Abstract: ABSTRACT: Tumor infiltration in the skeletal muscle is a rare entity and usually associated with aggressive tumor phenotype. Intramyofiber skeletal muscle invasion is the rarest pattern of muscle invasion, where the architecture of the individual myofibers remain preserved. This uncommon pattern of skeletal muscle invasion has occasionally been identified in Ewing sarcoma, non-Hodgkin lymphomas and leukemias however there are sparse literatures available on carcinomas showing intramyofiber pattern of invasion. They can closely mimic myositis and can be missed on low magnification. Thus, careful examination in high magnification supported by immunohistochemistry can resolve the issue. Here we present one case of intramyofiber skeletal muscle invasion in oral squamous cell carcinoma.

Source: Indian Journal of Pathology and Microbiology

DOI: 10.4103/ijpm.ijpm_880_22

Authors: Soumya Dey, Md Mohin, Moumita Sengupta, Uttara Chatterjee

Institution: Institute of Post Graduate Medical Education and Research

Language: English

Topic: Head and Neck Cancer Studies

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $200