Year: 2025
Type: article
Abstract: The increasing prevalence of obesity in domestic cats is closely linked to the emergence of diabetes mellitus, highlighting the need for early diagnostic tools. Obese cats typically show elevated leptin and reduced adiponectin levels—markers associated with early insulin resistance. Leptin resistance and compensatory hyperinsulinemia further reflect early metabolic dysfunction. These endocrine changes mirror those seen in humans and dogs, suggesting shared mechanisms across species. Incorporating these biomarkers into clinical practice could aid early risk stratification and preventive care. However, standardized reference ranges and cost-effective assays are still needed. This review assesses the predictive value of adiponectin, leptin, and insulin in identifying diabetes risk in obese cats.
Source: Frontiers in Animal Science
Authors: Laura Cernat, Sorana Daina, Adrian Macri
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,353
OpenAlex ID: W4413290362