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3′‐C‐Extended TNA: De Novo Synthesis, Enhanced Exonuclease Resistance, and Functional siRNA 3′‐Overhang Modifications Without Compromising Gene Silencing

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Year: 2025
Type: article
Source: Chemistry - A European Journal
DOI: 10.1002/chem.202502182
Authors: Yihang Gao, Chenghe Xiong, Chunlei Zhang, Junlin Wen, Xue Chen, Xia Li, Ziwen Dai, Lu Zhou, Hui Mei
Institutions: Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, University of Chinese Academy of Sciences, Shenzhen Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology
Language: English

Topic: RNA Interference and Gene Delivery
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: closed

Funders: Shenzhen Key Laboratory of Synthetic Genomics, National Key Research and Development Program of China, Basic and Applied Basic Research Foundation of Guangdong Province
Awards: G2966720941, G4310704303, G6781563475
OpenAlex ID: W4413290757
FWCI: 0.522
Cites: 50
Cited by: 2
Related to: 10
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