Work

The role of three-dimensional reconstruction in partial nephrectomy for ipsilateral multifocal renal tumors: a multicenter retrospective study

Year: 2025

Type: article

Abstract: PURPOSE: This study aims to evaluate the clinical impact of three-dimensional (3D) reconstruction in partial nephrectomy for ipsilateral multifocal renal tumors (MIRTs), focusing on surgical precision, ischemia management, and postoperative outcomes. METHODS: A retrospective analysis was performed on 56 MIRTs patients who underwent PN at two hospitals. Patients were divided into two groups: Group A (33 patients) received standard preoperative CT scans, while Group B (23 patients) underwent 3D reconstruction. Surgical data, including operative time, blood loss, ischemia time, and complications, were compared. Renal function was assessed using serum creatinine and eGFR levels preoperatively and postoperatively. RESULTS: Baseline demographics, including age, body mass index, preoperative hemoglobin levels, and tumor characteristics (size, multifocality), showed no significant intergroup differences (p > 0.05). The 3D reconstruction group demonstrated a 2.2 days reduction in hospital stay (9.43 vs. 11.63 days, p = 0.025) and achieved 100% adherence to preoperative surgical plans (vs. 81.9% in the 2D group, p = 0.037). Operative metrics, including operative time, estimated blood loss, ischemia time, and rates of collecting system injury, showed no significant differences (p > 0.05). Safety outcomes, such as conversion to radical nephrectomy (13.0% vs. 21.2%) and transfusion rates (8.6% vs. 9.1%), were comparable (p > 0.05). Postoperative renal function preservation, assessed by ΔeGFR and ΔSCr, also revealed no intergroup disparities (p > 0.05). CONCLUSION: Three-dimensional reconstruction technology enhances surgical precision and adherence to preoperative plans. It can be considered as a transformative tool in nephron-sparing surgery due to its potential to redefine standards for managing multifocal renal tumors.

Source: BMC Urology

DOI: 10.1186/s12894-025-01889-2

Authors: Peng Liu, Guanghao Chen, Zunmeng Sang, Yuanjie Niu

Institutions: Nankai University, Second Hospital of Tianjin Medical University, Qilu Hospital of Shandong University, Weifang People's Hospital, Tianjin Medical University

Language: English

Topic: Renal cell carcinoma treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,990