Work

Case Report: Carcinosarcoma of the common bile duct: a rare case report with literature review

Year: 2025

Type: article

Abstract: Carcinosarcoma of the common bile duct is an exceedingly rare and highly aggressive malignancy with uncertain therapeutic outcomes. We present a case of a 70-year-old Asian female presenting with progressive jaundice. Contrast-enhanced computed tomography (CT) identified a tumor in the common bile duct. The patient underwent successful radical pancreaticoduodenectomy, and postoperative histopathological analysis confirmed carcinosarcoma with predominant sarcomatoid differentiation. This report underscores the diagnostic challenges and therapeutic considerations for this rare entity, emphasizing the critical role of pathological confirmation.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1642467

Authors: Jia-qi Lou, Zhi-Wei Hu, Kun Liu, Ru-La A, Hao-Yu Fang

Institutions: Inner Mongolia Medical University, Inner Mongolia People's Hospital, Capital Medical University, Beijing Friendship Hospital

Language: English

Topic: Cholangiocarcinoma and Gallbladder Cancer Studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801