Individualized treatment of nasopharyngeal carcinoma with lung metastasis in an elderly patient: A case report
Year: 2025
Type: article
Study design: Case Report
Abstract: Nasopharyngeal carcinoma (NPC) is a common head and neck malignancy, particularly in southern China, with distant metastasis posing significant treatment challenges, particularly in elderly patients. This case report details the successful management of a 90-year-old male with NPC and lung metastasis. The patient underwent intensity-modulated radiotherapy for the nasopharyngeal tumor (70 Gy/35 fractions) with concurrent oral capecitabine, followed by stereotactic body radiotherapy (60 Gy/12 fractions) and immunotherapy (tislelizumab) for progressive lung lesions. Maintenance therapy with capecitabine was continued and the patient achieved stable disease with minimal adverse effects. This case highlights the efficacy of individualized multimodal therapy, including precision radiotherapy, chemotherapy and immunotherapy, in an elderly patient with NPC with metastasis, offering a potential framework for similar cases.
Source: Oncology Letters
Author: Tengteng Cai
Institution: Tongji University
Language: English
Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4413303030