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Divergent strength gains but similar hypertrophy after low-load and high-load resistance exercise training in trained individuals: many roads lead to Rome

Year: 2025

Type: article

Abstract: This study compared two distinct resistance exercise loading strategies (3-5 RM vs. 20-25 RM) in trained individuals, evaluating both muscular and myocellular adaptations. Our findings demonstrate that low-load resistance exercise training (LL-RET) is an effective alternative to traditional high-load strategies for increasing strength and muscle size. These results highlight that skeletal muscle growth can be achieved through various external loads, offering valuable insights for individuals seeking hypertrophy but unable to tolerate high loads.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00353.2025

Authors: Kristoffer Toldnes Cumming, Ingrid Cecelia Elvatun, Richard Kalenius, Gordan Divljak, Truls Raastad, Niklas Psilander, Oscar Horwath

Institutions: Østfold University of Applied Sciences, Norwegian School of Sport Sciences, Swedish School of Sport and Health Sciences, Karolinska Institutet

Language: English

Topic: Sports Performance and Training

Subfield: Orthopedics and Sports Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4413309990

FWCI: 0.949

Cites: 62

Cited by: 1

Related to: 10