Work

Fulcrum Occupancy–Leverage Perturbation Strategy Enables Rapid Discovery of Potent CDK2–Cyclin A2 Interaction Inhibitors

Year: 2025

Type: article

Source: Angewandte Chemie

DOI: 10.1002/ange.202513542

Institutions: Chinese Academy of Sciences, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, State Key Laboratory of Drug Research, Zhejiang University, Guiyang Medical University, East China Normal University

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Computational Theory and Mathematics

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Shanghai Municipal Health Commission, National Natural Science Foundation of China, Science and Technology Commission of Shanghai Municipality, National Key Research and Development Program of China, Program of Shanghai Academic Research Leader

Awards: G1042291103, G205348591, G270004384, G3114463410, G3637868774, G3679885010, G4322195117, G470197214, G4778903190, G6486158824, G793044578, G8567954048

OpenAlex ID: W4413310304

FWCI:

Cites: 55

Cited by:

Related to: 10