Catalytic asymmetric reactions of isocyanides for constructing non-central chirality
Year: 2025
Type: article
Abstract: Beyond the conventional carbon-centered chirality, catalytic asymmetric transformations of isocyanides have recently emerged as a powerful strategy for the efficient synthesis of structurally diverse scaffolds featuring axial, planar, helical, and inherent chirality. Herein, we summarize the exciting achievements in this rapidly evolving field. These elegant examples have been organized and presented based on the reaction type as well as the resulting chirality form. Additionally, we provide a perspective on the current limitations and future opportunities, aiming to inspire further advances in this area.
DOI: 10.3762/bjoc.21.129
Author: Jia-Yu Liao
Institution: Zhejiang University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4413311367