Work

Rafting toward a depression biomarker

Year: 2025

Type: article

Abstract: The journey from the cytoskeleton and G protein signaling to a framework that might provide a simple blood diagnostic for depression as well as a harbinger of individual antidepressant response, has been convoluted, occasionally frustrating, but ultimately rewarding. Herein, I provide a travelogue of sorts on our progress toward this end, and also chart a course toward the goal of providing a simple, quantitative and objective, biomarker-driven assessment tool that reflects the neurobiology of depressed mood.

Source: European Archives of Psychiatry and Clinical Neuroscience

DOI: 10.1007/s00406-025-02071-3

Author: Mark M. Rasenick

Institutions: University of Illinois Chicago, Jesse Brown VA Medical Center

Language: English

Topic: Treatment of Major Depression

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,990