Work

Brugada ECG pattern in a Caucasian patient with severe hypothyroidism

Year: 2025

Type: article

Abstract: Brugada syndrome (BrS) is a disorder leading to potentially life-threatening ventricular arrhythmias in patients with an apparently normal heart. It mostly affects men of Asian descent, and the prevalence varies between ethnicities. Typical ECG abnormalities with no symptoms are referred to as the Brugada pattern, and hypothyroidism is a potential trigger of this. We report on a Caucasian man with severe hypothyroidism and Brugada ECG pattern, which normalised after starting replacement therapy. The association has been previously described in only a few patients. LEARNING POINTS: Brugada syndrome (BrS) is a potentially life-threatening disease that can be easily recognized on the electrocardiogram (ECG). Typical ECG abnormalities associated with no clinical symptoms is referred to as the Brugada pattern.Many studies have underscored the association between hypothyroidism and Brugada ECG pattern, that can be reversed by a prompt initiation of replacement therapy.

Source: European Journal of Case Reports in Internal Medicine

DOI: 10.12890/2025_005544

Authors: Erminia De Cristofaro, Maria Giulia Canè, Davide Cunzi, Giorgia Prampolini, Silvia Daniela Umbertina Fedeli, Aurelio Negro

Institution: Azienda Sanitaria Unità Locale di Reggio Emilia

Language: English

Topic: Cardiac electrophysiology and arrhythmias

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $323