Work

Lipid accumulation product index and TG/HDL-C as a predictor for insulin resistance in diabetes mellitus - A cross-sectional pilot study

Year: 2025

Type: article

Abstract: Background: The prevalence of type 2 diabetes mellitus (T2DM) is mounting over the world and said to be directly proportional to obesity. It is known that Lipid Accumulation Product Index (LAPI) in T2DM is related with insulin resistance and inflammation. Materials and Methods: An analytical cross-sectional study in 30 patients was done. Result: The correlation analysis revealed a positive non-significant correlation between IR and Triglyceride; HOMA-IR and HDL: Negative correlation (-0.202), but not statistically significant (p = 0.142). HOMA-IR and LAPI: Positive correlation (0.335), statistically significant (p = 0.035). Also, the predictors TG and HDL do not have a statistically significant impact on HOMA -IR and LAPI. The data is suggestive of positive correlation between IR and LAPI suggests a potential link between IR and LAPI. Conclusion: We can conclude that clinical protocols for screening may incorporate LAPI in patients with diabetes for prediction of long term complications like cardiovascular episode.

Source: Panacea Journal of Medical Sciences

DOI: 10.18231/pjms.v.15.i.2.414-417

Authors: Palak Hemrajani, Madhur Gupta, Arti Kasulkar, Harsh Salankar, Kedar Deshpande

Institutions: NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital, Government Medical College

Language: English

Topic: Diabetes, Cardiovascular Risks, and Lipoproteins

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $48