In vitro and in vivo degradation behavior of a corrosion-resistant Mg alloy with combined addition of rare-earth elements
Year: 2025
Type: article
Abstract: The in vitro and in vivo degradation behavior of an experimental Mg alloy with high corrosion resistance has been investigated and compared with that of a commercial AZ31 Mg alloy with a similar chemical composition. In vitro tests indicated that the experimental alloy is >2.5 times more resistant to degradation than AZ31 during immersion in HBSS at 37 °C for 72 h. In vivo tests in the femoral vein of a mouse confirmed that the former degrades much more slowly and uniformly in the biological environment than the latter. Compared with WE43 and JDBM alloys, which are currently considered promising candidates for Mg-based biodegradable materials, the experimental alloy in this study showed better degradation resistance with a similar level of biocompatibility. Microstructural and electrochemical factors affecting the degradation behavior of the alloys in this study are also discussed.
Source: Journal of Magnesium and Alloys
Authors: Du-Won Min, Young Hee Kim, Jaeho Kwon, Jeong-Ki Kim, Cholong Choi, Eunhye Yun, Chaenyung Cha, Seong Hoon Choi, Hojong Park, Jung Gu Lee, Byungsuk Kwon, Sang Jun Park, Sung Soo Park
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,500
Awards: G5069871617, G6693974757, G822474692
OpenAlex ID: W4413323717