Year: 2025
Type: preprint
Abstract: Objective To assess the reliability of antepartum cardiotocography (CTG) pattern identi-fication by quantifying the level of agreement among expert clinicians and between clinicians and the Dawes–Redman (DR) computerised system, particularly in the context of limited formal guidelines and the known subjectivity of antepartum assessments. The findings are intended to support improvements in training and the standardization of CTG interpretation. Methods Five senior clinicians with expertise in fetal monitoring independently annotated 105 15-minute fetal heart rate (FHR) traces using structured web-based software. For each trace, participants identified the baseline, accelerations and decelerations and categorised variability. Inter-observer agreement was assessed using intraclass correlation (ICC) for baselines and Fleiss’ κ for variability. Sensitivity and positive predictive value (PPV) for acceleration and deceleration detection were calculated relative to majority-voted results. The DR algorithm was used to identify the same patterns and the output was compared against the clinical consensus annotations. Results Baseline agreement was excellent among participants (ICC = 1.0, 95% CI 1.00– 1.00). Variability classifications showed only moderate concordance (Fleiss’ κ = 0.39, 95% CI − 0.01–0.56). Detection of accelerations and decelerations varied across clinicians (sensitivity 39.2–97.2%, PPV 39.7–91.3%). The DR system showed good agreement for accelerations (sensitivity = 64.8%, 95% CI 57.1–72.1%; PPV = 85.0%, 95% CI 79.5–89.8%) but poor agreement for decelerations (sensitivity = 50.0%, 95% CI 14.3–75.0%; PPV = 20.0%, 95% CI 4.2–39.1%). DR-classified variability showed minimal agreement with clinical ratings (Fleiss’ κ = 0.002, 95% CI − 0.007–0.027). Conclusions Antepartum CTG interpretation remains inconsistent for identification of decelerations and variability. While baseline assessment appears robust, current clinical and algorithmic approaches show limited agreement for more ambiguous patterns. These findings support the need for updated training and refined algorithms to improve reliability in antepartum fetal surveillance.
Source: medRxiv
Institution: University of Oxford
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4413329020
