Work

Foreign Body Granuloma After Polylactic Acid Filler Injection for Penile Girth Enhancement: Three Cases Report

Year: 2025

Type: article

Abstract: Penile girth enhancement is achieved using a variety of fillers, including autologous fat injection, silicone, collagen, hyaluronic acid, polylactic acid (PLA), polymethylmethacrylate, and dextran. While PLA has a good filling effect due to its bio-stimulatory properties, it may cause complications in a certain percentage of cases. We describe three patients who developed granulomatous reactions at least 2 months after receiving subcutaneous injections of PLA-based fillers. In two of the three cases, surgical removal of the infiltrate was necessary due to insufficient response to conservative treatment. Histological examination revealed unspecific chronic granulomatous inflammation of soft tissues. Based on these cases, we conclude that the causes of granuloma formation and ways to prevent it still require further research. Aesthetic specialists should carefully select patients, materials, and application techniques. Patients should be informed about the possible complications of penile girth enhancement.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.70811

Authors: Mykola Boiko, Oleksandr Boiko, Serhiy Pasyechnikov, Mykola Notsek

Institutions: Hospital de Cruces, Bogomolets National Medical University, Kyiv International University

Language: English

Topic: Facial Rejuvenation and Surgery Techniques

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820