Work

Recurrent Nonbacterial Thrombotic Endocarditis after Vegetectomy of Bioprosthetic Mitral Valve

Year: 2025

Type: article

Abstract: We report a case of recurrent nonbacterial thrombotic endocarditis (NBTE) following vegetectomy of bioprosthesis without malignancy or autoimmune disorders. A 76-year-old woman underwent mitral valve replacement with a bioprosthesis for mitral regurgitation. Six years later, an outpatient echocardiography revealed a mobile vegetation incidentally. No signs of infection were observed, and various tests ruled out malignancy or autoimmune disorders. Pathological findings after an urgent vegetectomy also showed no signs of infection, and the diagnosis was NBTE. Anticoagulation therapy with warfarin was continued, but 1 year after surgery, an outpatient echocardiography revealed NBTE recurrence. After the patient underwent anticoagulation therapy with heparin and resection of the papilloma of the maxillary sinus, the vegetation disappeared, and there has been no recurrence. Since NBTE can recur, strict lifelong follow-up with anticoagulation therapy might be required.

Source: Interdisciplinary CardioVascular and Thoracic Surgery

DOI: 10.1093/icvts/ivaf192

Authors: Taro Nakazato, Matsuda Yasuhiro, Tatsuya Ozaki, Mutsunori Kitahara

Institution: Kansai Rosai Hospital

Language: English

Topic: Infective Endocarditis Diagnosis and Management

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,258