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Lenvatinib‐Associated Non‐Tuberculous Mycobacterial Pulmonary Disease: A Case Report

Year: 2025

Type: article

Abstract: ABSTRACT A 64‐year‐old man, with a history of hepatocellular carcinoma and long‐term oral lenvatinib treatment, was hospitalised in our institution twice due to ‘cough’. During hospitalisation, the patient underwent multiple bronchoscopies, with lavage fluid sent for pathogen testing, which returned negative results. Finally, Mycobacterium kansasii was detected via next‐generation sequencing (NGS). Considering the patient's poor hepatic reserve, we decided against initiating targeted antimicrobial therapy and discontinued lenvatinib. Two months after stopping lenvatinib, the patient's symptoms of cough and chest tightness improved. A follow‐up chest computed tomography (CT) on March 18, 2025, showed resolution of the lesions.

Source: Respirology Case Reports

DOI: 10.1002/rcr2.70316

Authors: Qian Wang, Lili Du, Yiming Wang, Longhui Zhang

Language: English

Topic: Mycobacterium research and diagnosis

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,130

OpenAlex ID: W4413338129

FWCI:

Cites: 11

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Related to: 10