Work

Commentary on “HDL‐C/LDL‐C Ratio and All‐Cause Mortality in Populations at High CVD Risk: A Prospective Observational Cohort Study”

Year: 2025

Type: editorial

Abstract: Lin and colleagues leveraged the 32,609-participant Fu-CARE cohort to report a U-shaped association between the high-densitylipoprotein-cholesterol/low-density-lipoprotein-cholesterol (HDL-C/LDL-C) ratio and all-cause mortality, with the lowest risk at 0.30-0.50[1].Their large sample and sex-specific restricted-cubicspline modeling deserve praise, but several methodological issues temper causal inference and translational value.

Source: Chronic Diseases and Translational Medicine

DOI: 10.1002/cdt3.70019

Authors: Naghmeh Ziaie, Mohammad Barary, Soheil Bakhshinasab, Romina Hamzehpour, Soheil Ebrahimpour

Institutions: Babol University of Medical Sciences, Shahid Beheshti University, Shahid Beheshti University of Medical Sciences

Language: English

Topic: Lipoproteins and Cardiovascular Health

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Babol University of Medical Sciences

OpenAlex ID: W4413350023

Cites: 9

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Related to: 10