[Clinical and immunological features for early differentiation between primary immune thrombocytopenia and connective tissue disease in children].
Year: 2025
Type: other
Abstract: OBJECTIVES: To investigate the clinical and immunological features of children with primary immune thrombocytopenia (pITP) or connective tissue disease (CTD) with thrombocytopenia as the initial manifestation at initial diagnosis, and to provide a basis for early differentiation. METHODS: A retrospective study was performed on 236 children with pITP (pITP group) or CTD with thrombocytopenia as the initial manifestation (CTD-TP group) who were admitted from January 2019 to August 2024. Clinical and immunological indicators were compared between the two groups to identify potential influencing factors for early differentiation and their discriminative validity. RESULTS: <0.05). CONCLUSIONS: There is heterogeneity in the clinical and immunological indicators between children with pITP and CTD-TP at initial diagnosis, and these research findings can help with the early differentiation between the two diseases.
Source: PubMed
Authors: Fu-Rong Kang, Mei Yan, Ying-Bin Yue, Hailiguli Nuriddin, Yong-Feng Cheng, Yu Liu
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4413369528