Anthelmintic efficacy of Lippia alba essential oil against gastrointestinal nematodes in goats
Year: 2025
Type: article
Abstract: This study aimed to evaluate the anthelmintic efficacy of Lippia alba essential oil against gastrointestinal nematodes in goats, identify the helminth genera present, and perform a chemical characterization of the tested oil. Fecal samples were collected and quantified using the McMaster technique; samples with counts above 200 eggs per gram (EPG) were included in the experiment. The pooled positive sample showed an EPG of 2800. Quantitative coproculture was conducted with a negative control group (distilled water) and L. alba essential oil at concentrations of 10 mg/mL, 25 mg/mL, 50 mg/mL, and 100 mg/mL, maintained at room temperature for 10 days. Subsequently, larvae were recovered, identified, and quantified. Treatment efficacy was assessed using the larval reduction formula. Concentrations of 25 mg/mL, 50 mg/mL, and 100 mg/mL were effective, achieving larval reductions of 79.5%, 87.8%, and 89.8%, respectively. The genera identified included Haemonchus sp. (56.8%), Trichostrongylus sp. (42.9%), and Oesophagostomum sp. (0.3%). Chemical composition of the oil was analyzed using gas chromatography-mass spectrometry with an advanced electron ionization source. Twenty-five compounds were identified, with E-citral (23.76%), Z-citral (20.46%), carvone (10.92%), and limonene (6.40%) being the most abundant. All tested concentrations of L. alba essential oil, except 10 mg/mL (29.7%), demonstrated anthelmintic potential by significantly reducing gastrointestinal nematode larvae in goats.
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
SDG: Zero hunger
Open Access status: diamond
OpenAlex ID: W4413372649