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HerTACs Enable Tumor‐Selective Lysosomal Degradation of Membrane and Extracellular Proteins via HER2 Trafficking

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Year: 2025
Type: article
Source: Angewandte Chemie International Edition
DOI: 10.1002/anie.202511467
Authors: Shipeng He, Wenjing Huang, Yaojin Zhu, Fei Gao, Yuxin Fang, Jiayi Zhu, Yuhan Bao, Guoqiang Dong, Chunquan Sheng
Institutions: Shanghai University, Second Military Medical University
Language: English

Topic: Protein Degradation and Inhibitors
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Shanghai Rising-Star Program, National Key Research and Development Program of China
Awards: G254463811, G270790173, G628024959, G6519793249
OpenAlex ID: W4413374489
FWCI: 4.821
Cites: 55
Cited by: 19
Related to: 10
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