Year: 2025
Type: article
Abstract: Most metal organic cages are assembled through metal–ligand coordination, resulting in cages where the metal ions are part of the cage architecture, and thus have limited reactivity. There are only a handful of metal organic cages produced by metalation of a pre‐synthesised organic cage. In this work, we show that hexa‐cationic hydrazone cages coordinate a range of transition metal ions upon deprotonation to give cage complexes with metal ions oriented towards the cage cavity. Remarkably, a cage with ethyl solubilising groups gives the expected three‐fold symmetric metallocage, cages with alkoxy solubilising groups give low‐symmetry zinc metallocages, and a cage without a solubilising group switches between high and low symmetry conformations depending on solvent. These low symmetry arrangements persist on the NMR timescale at temperatures as high as 360 K and in the presence of a wide range of anions.
Source: Angewandte Chemie
Institution: Australian National University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $5,790
OpenAlex ID: W4413374585