Work

Schizotypy 17 years on: Long-range endophenotype forecasting of psychotic symptoms using perceptual aberrations and sustained attention.

Year: 2025

Type: article

Abstract: ') on a measure of sustained attention, from the Continuous Performance Test-Identical Pairs version (Cornblatt et al., 1989), significantly predicted the presence of psychotic symptoms at age 35. The 17-year predictive associations remained significant even when considered jointly with mental state variables present at age 18. The results support the validity of endophenotypes, the psychometric high-risk method, and the general schizotypy model of schizophrenia. Finally, as long conjectured, the results provide support for a deficit in sustained attention as a predictor of psychotic symptoms over time. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

Source: Journal of Psychopathology and Clinical Science

DOI: 10.1037/abn0001039

Author: Mark F. Lenzenweger

Institution: Binghamton University

Language: English

Topic: Schizophrenia research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Cornell University, Research Foundation for the State University of New York, Binghamton University