Figure S7 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
Year: 2025
Type: other
Abstract: SMARCA4 loss leads BRCA1 recruitment and R-Loop accumulation associated with paused Pol II
Authors: Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, Jutta Steinberger, Selim Misirlioglu, Nicklas Bassani, Racim Sansal, Amber Yasmeen, Geneviève Morin, Jingjie Guo, Anie Monast, Virginie Pilon, Alica Valachová, Kitty Pavlakis, Lili Fu, Walter H. Gotlieb, W. Glenn McCluggage, David Huntsman, Alexander J.R. Bishop, Douglas A. Levine, Morag Park, Yemin Wang, Brian Raught, William D. Foulkes, Sidong Huang
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4413380763