Work

Case Report: Syndrome of inappropriate antidiuretic hormone secretion induced by pramipexole: a case report and literature review

Year: 2025

Type: article

Abstract: Pramipexole, a novel dopamine receptor agonist, is widely used in the treatment of Parkinson's disease and related syndromes. While studies have demonstrated that pramipexole can cause various adverse reactions, primarily involving the central nervous system or gastrointestinal symptoms, there remains limited reporting on pramipexole-induced syndrome of inappropriate antidiuretic hormone secretion (SIADH). This article analyzes and discusses a case of pramipexole-induced SIADH that occurred in our hospital. At the same time, we also summarize and discuss all current cases of pramipexole-induced SIADH. We anticipate these findings will serve as a valuable clinical reference to guide appropriate medication use.

Source: Frontiers in Pharmacology

DOI: 10.3389/fphar.2025.1627245

Authors: Ke-Qian Chen, Xiang Liu, Hai-Bo Lei

Institution: Hunan University

Language: English

Topic: Electrolyte and hormonal disorders

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801