Work

Emergence and Competing Selectivity of Minimal Self‐Assembly Lipoamino Acids

Year: 2025
Type: article
Abstract: Designing synthetic chemical systems capable of mimicking life‐like behavior surely will help to understand the basic principles sustaining life, but also to create advanced materials potentially going beyond nature. Herein, we report the synthesis of a family of lipoamino acids from their individual components, which are free amino acids and lipid precursors, that allow us to study competition and selection in their formation. Octanoyl‐ L ‐histidine outcompetes from a pool of natural amino acids and a family of lipids, emerging as the fittest, where the observed selectivity is the result of a very efficient autocatalytic mechanism.
Language: English
Open Access status: hybrid
Estimated APC paid: $4,030
OpenAlex ID: W4413382482
FWCI: 0.968
Cites: 27
Cited by: 2
Related to: 10