Year: 2025
Type: article
Abstract: With the continuous development of gene therapy technology, an efficient gene delivery system has become the key to realizing gene therapy. Traditional gene delivery methods have many limitations, such as low transfection efficiency and high cytotoxicity. As a new type of gene delivery vector, multifunctional nanocomposites have shown great application potential due to their unique physical and chemical properties and biocompatibility. This paper aims to study the application of multifunctional nanocomposites in gene delivery through the analysis of relevant cases and the discussion of their mechanism of action to understand their advantages and challenges in gene therapy deeply. The results show that the multifunctional nanocomposites can effectively improve gene transfection efficiency, reduce cytotoxicity, and achieve targeted gene delivery. In addition, its application in the treatment of different diseases has been explored. The research significance of this paper is to provide a theoretical basis and practical guidance for the further development of multifunctional nanocomposites in the field of gene therapy and promote the clinical application of gene therapy technology.
DOI: 10.54097/zg390z62
Author: Yiting Wang
Institution: Shanghai University of Finance and Economics
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4413401160