Year: 2025
Type: article
Abstract: Rhodanine derivatives, as a subtype of thiazolidin-4-ones, represent an important class of heterocyclic compound known for their broad spectrum of biological activities and practical applications. In this short note, the synthesis of a new compound, 5-[2-(4-chlorophenyl)-2-oxoethyl]-3-(4-hydroxyphenyl)-2-thioxo-1,3-thiazolidin-4-one, is described. The target molecule was synthesized via a thia-Michael addition followed by cyclocondensation. Its structure was confirmed by 1H and 13C NMR spectroscopy and further supported by 2D NMR studies.
Source: Molbank
DOI: 10.3390/m2049
Author: Nazar Trotsko
Institution: Medical University of Lublin
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $603
OpenAlex ID: W4413402239