Work

Carboxytherapy in the Management of Selected Skin Conditions–Applications in Monotherapy and Combined Treatments

Year: 2025

Type: article

Abstract: Carboxytherapy is a non-invasive therapeutic method involving the transcutaneous or subcutaneous administration of carbon dioxide (CO2), which stimulates microcirculation, neoangiogenesis, and collagen production. This narrative review summarizes the latest scientific findings (2020–2025) on the effectiveness of carboxytherapy in treating selected dermatological and aesthetic skin conditions, including periorbital dark circles, stretch marks, scars, and signs of skin aging. The article discusses both monotherapies and combination protocols, particularly with laser therapies and chemical peels. Numerous clinical studies confirm that carboxytherapy significantly improves skin elasticity, tone, hydration, and structure through mechanisms such as improved oxygenation, stimulation of fibroblasts, and controlled inflammation. Moreover, combination therapies frequently offer superior outcomes, especially in scar and stretch mark reduction. Carboxytherapy demonstrates high safety, minimal side effects, and broad applicability, making it a valuable tool in both medical and cosmetic dermatology.

Source: Applied Sciences

DOI: 10.3390/app15179236

Authors: Sylwia Jarząbek-Perz, Małgorzata Wrzosek

Institutions: Jan Kochanowski University, Medical University of Warsaw

Language: English

Topic: Dermatologic Treatments and Research

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,896