Consensus Statements on Airway Clearance Interventions in Intubated Critically Ill Patients—Protocol for a Delphi Study
Year: 2025
Type: article
Study design: Study Protocol
Abstract: Intubated critically ill patients are susceptible to secretion accumulation because of compromised airway clearance. Various airway clearance interventions are employed to prevent complications arising from mucus retention. This Delphi study aims to collect global opinions in an international expert panel of ICU professionals on the usefulness of these various airway clearance interventions. A steering committee performed a literature search informing the formulation of statements. Statements are grouped into two distinct parts: (1) Humidification and Nebulization, and (2) Suctioning and Mucus mobilization techniques. For each part, a diverse panel of 30–40 experts will be selected, with concerted effort to involve experts from various medical specialties involved in airway clearance methods. Multiple choice questions (MCQs) or 7-point Likert-scale statements will be used in the iterative Delphi rounds to reach consensus on various airway clearance interventions. Rounds will continue until stability is achieved for all statements. Consensus will be deemed achieved when a choice in MCQs or a Likert-scale statement achieves ≥75% agreement or disagreement. Starting from the second round of the Delphi process, stability will be assessed using non-parametric χ2 tests or Kruskal–Wallis tests. Stability will be defined by a p-value of ≥0.05.
Source: Life
DOI: 10.3390/life15081292
Institutions: Amsterdam University Medical Centers, New Cross Hospital, The Royal Wolverhampton NHS Trust, Royal Perth Hospital, Ospedale Policlinico San Martino, University of Genoa, Max Super Speciality Hospital, Université de Tours, Inserm, Centre Hospitalier Universitaire de Tours, Clinical Investigation Center Plurithematic Tours, Centre d'Étude des Pathologies Respiratoires, Mahidol University, University of Oxford, Mahidol Oxford Tropical Medicine Research Unit, Medical University of Vienna, Amsterdam University of Applied Sciences
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,137
Funder: ZonMw
Awards: G8041098685, G972038897
OpenAlex ID: W4413416751
