Work

Impact of Change in Neonatal Resuscitation Program Guidelines for Infants Born Through Meconium-Stained Amniotic Fluid

Year: 2025

Type: article

Abstract: Background: In 2016, the neonatal resuscitation program (NRP) withdrew its recommendation to perform endotracheal suctioning in non-vigorous neonates born through meconium-stained amniotic fluid (MSAF). The objective of this study is to compare outcomes in non-vigorous neonates born through MSAF before and after the change in NRP’s recommendations. Methods: This is a retrospective cohort study in a single center assessing all neonates ≥34 weeks of gestation with MSAF in 2010-2015 (pre-implementation of new guidelines) and 2017-2022 (post-implementation of new guidelines). Results: Neonates receiving tracheal suctioning were more likely to be diagnosed with MAS (29.3% vs. 19.7%; P=0.03) and PPHN (8.9% vs. 2.5%; P=0.003), and more likely to receive surfactant (7.6% vs. 3.2%; P=0.03). Conclusion: In our institution, non-vigorous neonates born via MSAF after the change in NRP guidelines were less likely to be diagnosed with MAS and PPHN and were less likely to receive surfactant. Our study supports current NRP guidelines.

Source: Children

DOI: 10.3390/children12081072

Authors: Hamza Abbasi, James Shelton, Praveen Chandrasekharan, Munmun Rawat

Institution: University at Buffalo, State University of New York

Language: English

Topic: Neonatal Respiratory Health Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,896