Work

Nonketotic hyperglycemic hemichorea: white shadows on CT and T1-weighted MRI

Year: 2025

Type: article

Abstract: Nonketotic hyperglycemic hemichorea (NHH) is a rare movement disorder, most commonly observed in elderly female patients with poorly controlled diabetes. We describe a 55-year-old male patient with diabetes who was admitted due to involuntary movements of the right limbs for five days. CT revealed a hyperdense lesion in the left putamen and caudate nucleus, while MRI showed hyperintensity on T1WI and hypointensity on both T2WI and diffusion-weighted imaging. The patient was treated with oral haloperidol and insulin for blood glucose control, leading to gradual symptom improvement. Follow-up imaging showed resolution of the lesions, correlating with clinical improvement. NHH has characteristic imaging findings and should be differentiated from cerebral hemorrhage, basal ganglia calcification, and hepatic encephalopathy.

Source: Journal of Radiation Research and Applied Sciences

DOI: 10.1016/j.jrras.2025.101890

Authors: Zhihui Zhou, Juan Peng, Wenxiao Zhang, Jinming Deng, Libin Liu

Institutions: Guangdong Medical College, Zhuhai People's Hospital, Jinan University

Language: English

Topic: Neurological and metabolic disorders

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,400