Work

Physiological State Recognition via HRV and Fractal Analysis Using AI and Unsupervised Clustering

Year: 2025

Type: article

Abstract: Early detection of physiological dysregulation is critical for timely intervention and effective health management. Traditional monitoring systems often rely on labeled data and predefined thresholds, limiting their adaptability and generalization to unseen conditions. To address this, we propose a framework for label-free classification of physiological states using Heart Rate Variability (HRV), combined with unsupervised machine learning techniques. This approach is particularly valuable when annotated datasets are scarce or unavailable—as is often the case in real-world wearable and IoT-based health monitoring. In this study, data were collected from participants under controlled conditions representing rest, stress, and physical exertion. Core HRV parameters such as the SDNN (Standard Deviation of all Normal-to-Normal intervals), RMSSD (Root Mean Square of the Successive Differences), DFA (Detrended Fluctuation Analysis) were extracted. Principal Component Analysis was applied for dimensionality reduction. K-Means, hierarchical clustering, and Density-based spatial clustering of applications with noise (DBSCAN) were used to uncover natural groupings within the data. DBSCAN identified outliers associated with atypical responses, suggesting potential for early anomaly detection. The combination of HRV descriptors enabled unsupervised classification with over 90% consistency between clusters and physiological conditions. The proposed approach successfully differentiated the three physiological conditions based on HRV and fractal features, with a clear separation between clusters in terms of DFA α1, α2, LF/HF, and RMSSD (with high agreement to physiological labels (Purity ≈ 0.93; ARI = 0.89; NMI = 0.92)). Furthermore, DBSCAN identified three outliers with atypical autonomic profiles, highlighting the potential of the method for early warning detection in real-time monitoring systems.

Source: Information

DOI: 10.3390/info16090718

Authors: Galya Georgieva-Tsaneva, Krasimir Cheshmedzhiev, Yoan-Aleksandar Tsanev, Miroslav Dechev

Institutions: Bulgarian Academy of Sciences, Institute of Robotics, Technical University of Varna

Language: English

Topic: Heart Rate Variability and Autonomic Control

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,930