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Low-Dose Interleukin-2 Therapy: A Transformative Approach for the Management of Autoimmune Complications Associated with Streptococcus pyogenes Infections

Year: 2025

Type: conference-paper

Abstract: Acute rheumatic fever is an autoimmune inflammatory reaction to Streptococcus pyogenes infections, leading to progressive heart valve damage and rheumatic heart disease (RHD) [...]

DOI: 10.3390/proceedings2025124021

Authors: Ailin Lepletier, Rukshan Ahamed Mohamed Rafeek, Despena Vedis, Harshi Weerakoon, Natkunam Ketheesan, Michael F. Good, Manisha Pandey

Institutions: Griffith University, University of New England, Rajarata University of Sri Lanka

Language: English

Topic: Streptococcal Infections and Treatments

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Funders: University of New England, Griffith University, National Health and Medical Research Council

Awards: Novel vaccine technology to translate knowledge of immuno-pathogenesis into vaccines and therapeutics, Preclinical evaluation of a streptococcal peptide based specific diagnostic for rheumatic fever and the identification of proteins responsible for the pathogenesis of rheumatic heart disease, Enhancing vaccine immunity: modelling with Streptococcus

OpenAlex ID: W4413430243

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