Crohn's disease of the appendix. Late outcome of surgery after 37 years (clinical case and review)
Year: 2025
Type: article
Study design: Case Report
Abstract: OBJECTIVE: based on the analysis of our own clinical observation and literature review, to consider the problem of treatment of Crohn's disease of the appendix. PATIENT AND METHODS: the long-term result (37 years old) of a patient who underwent right-sided hemicolectomy for Crohn's disease of the appendix at the age of 28 is presented. During these years, she did not receive treatment for this disease. In 2024, a comprehensive clinical, instrumental, and molecular genetic study was conducted. RESULTS: According to the results of the examination, no data were found for the recurrence of Crohn's disease, however, a molecular genetic study revealed 2 clinically significant genotypes associated with the risk of Crohn's disease. A review of domestic and foreign literature is presented, including the role of the intestinal mesentery in the pathogenesis of Crohn's disease. CONCLUSION: in the isolated form of Crohn's disease of the appendix, appendectomy is an acceptable surgical treatment option; if the base of the appendix is affected and the cecum dome is involved, colon resection options should be considered. Surgical interventions lead to recovery/long-term remission.
Source: Koloproktologia
Authors: V. M. Timerbulatov, Sh. V. Timerbulatov, L. R. Aitova, D. V. Lopatin, A. R. Gafarova, R. R. Akhmerov, I. D. Gayazov
Institution: Bashkir State Medical University
Language: English
Topic: Inflammatory Bowel Disease
Subfield: Genetics
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4413442167