Work

Recent advances and applications of miniaturized analytical- and on-line sample preparation- columns

Year: 2025

Type: article

Abstract: • Current miniaturized column technology was presented and discussed. • Recent advances and applications for trap columns were reviewed. • The most recent achievements based on miniaturized LC were discussed. • Recent CE/CEC applications were presented. • Applications of MIP columns were reviewed. Miniaturized columns are chromatographic columns used in modern LC applications, which are in narrow diameter format while CE/CEC separations with miniaturized columns show high separation efficiency due to flat flow profile from EOF. There are several variants of miniaturized columns with both analytical- and trap columns. This review summarizes and discusses recent advances and applications on miniaturized analytical- and on-line sample preparation- columns focussing on literature mostly between 2019 and 2024.

Source: Journal of Chromatography Open

DOI: 10.1016/j.jcoa.2025.100247

Authors: Cemil Aydoğan, Zeynep Günyel, Ashraf Ali, Ilgım Göktürk, Fatma Yılmaz, Adil Denizli

Institutions: Bingöl University, Henan University of Technology, Hacettepe University, Bolu Abant İzzet Baysal University

Language: English

Topic: Analytical Chemistry and Chromatography

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,360

Funder: Türkiye Bilimsel ve Teknolojik Araştırma Kurumu