Work

Uncommon Manifestations of Newly Diagnosed B-cell Chronic Lymphocytic Leukemia Prompting the Concurrent Diagnosis of Advanced Prostate Cancer: A Case Report

Year: 2025

Type: article

Abstract: Patients with chronic lymphocytic leukemia (CLL) have an increased risk for developing secondary malignancies (SMs), which usually follow an aggressive clinical course and are associated with unfavorable survival rates. Herein, we describe a patient diagnosed with CLL, who also presented with uncommon findings such as extremely elevated alkaline phosphatase levels, abnormal coagulation studies, and leucoerythroblastic reaction, that ultimately resulted in the diagnosis of concurrent metastatic prostate cancer. Early recognition of findings indicative of SM in CLL patients, even during early stages, is crucial, and physicians should stay alert. Furthermore, CLL patients should undergo more frequent screening tests for cancer as compared to the general population.

Source: Cureus

DOI: 10.7759/cureus.90223

Authors: Christos Stafylidis, Iraklis Patsialos, Dimitra Stefanou, Eleftheria Lakiotaki, Panagiotis Diamantopoulos

Institutions: National and Kapodistrian University of Athens, Laiko General Hospital of Athens

Language: English

Topic: Multiple and Secondary Primary Cancers

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4413451973