Work

Elaboration and profiling of the first OSBP degrader issued from natural Schweinfurthins

Year: 2025

Type: article

Source: Bioorganic Chemistry

DOI: 10.1016/j.bioorg.2025.108909

Authors: Carole Guimard, Gwenaëlle Jézéquel, Anne-Sophie Gay, Laurie Askenatzis, Joëlle Bigay, Bruno Antonny, Hélène Levaique, Emilie Mérour, Jérôme Bignon, Bruno Mesmin, Sandy Desrat, Fanny Roussi

Institutions: Centre National de la Recherche Scientifique, Institut de Chimie des Substances Naturelles, Université Paris-Saclay, Inserm, Université Côte d'Azur, Institut de Pharmacologie Moléculaire et Cellulaire

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Vietnam Academy of Science and Technology, Agence Nationale de la Recherche, Université Paris-Saclay, Groupement des Entreprises Françaises dans la lutte contre le Cancer, Ecoles doctorales, Université Paris-Saclay

Awards: Idex Paris-Saclay, G311888100

OpenAlex ID: W4413466195

FWCI: 0.24

Cites: 46

Cited by: 1

Related to: 10