Work

Atypical teratoid rhabdoid tumor of lumbar spine in a child, masquerading as ependymoma

Year: 2025

Type: article

Abstract: Atypical teratoid/rhabdoid tumors (ATRT) are rare embryonal tumors of the central nervous system system (CNS) which predominantly occur in children less than three years of age and accounts for 1–2% of all pediatric CNS malignancies, most commonly in intracranial locations. The spinal cord is a rare primary site of ATRT with a prevalence of only 2% of all CNS ATRT, with few case reports. We report the case of an 8-yeat-old child initially thought to have lumbar spinal ependymoma, based on clinical presentation and imaging. However careful neuropathology review, with comprehensive immuno-histochemistry, confirmed the diagnosis of spinal ATRT. The child was treated with radiation therapy and adjuvant chemotherapy, and continues to do well.

Source: Pediatric Hematology Oncology Journal

DOI: 10.1016/j.phoj.2025.100488

Authors: Swagatika Samal, Ajitesh Avinash, Subhasis Mishra, Saroj Prasad Panda, Soubhagya Ranjan Tripathy

Institutions: Siksha O Anusandhan University, Institute of Medical Sciences and Sum Hospital

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600