Antioxidant administration on the incidence of preterm premature rupture of membranes: a literature review
Year: 2025
Type: article
Abstract: One of the obstetric issues that can lead to consequences for both the mother and the unborn child is premature rupture of membranes (PROM). In Indonesia, 35% of pregnancies ended in preterm rupture of the membranes in 2013. The incidence of preterm pregnancy is 2% of all pregnancies, while the incidence of term pregnancy ranges from 6 to 19%. At 37 weeks gestation, the phrase "premature rupture of membranes" is used. Preterm premature rupture of membranes (PPROM) is the term used to describe when the membranes burst before birth in women whose gestational age is less than 37 weeks. It is believed that the pathophysiology of premature membrane rupture involves reactive oxygen species (ROS). The result of premature membrane rupture is anticipated to be impacted by antioxidant supplementation.
Authors: I Gde Sastra Winata, Prayascita Mahendrata, Anak Agung Ratih Kusumadewi Wiraputri, Meirisa Afifah Nurmalia Anwar, Jessica Nathalia
Institution: Udayana University
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4413485184