Work

Congenital solitary neck ulcer as a presentation of Langerhans cell histiocytosis

Year: 2025

Type: article

Abstract: Langerhans cell histiocytosis (LCH) is a neoplasm originating from immature haematopoietic myeloid precursor cells. It may uncommonly present with congenital ulcers. We report a case of a neonate admitted with a fever and a purulent congenital ulcer at the base of the neck, who, in the investigations, was diagnosed with LCH. This case highlights the importance of considering LCH in persistent, treatment-resistant cutaneous lesions in neonates and the necessity for biopsy and continuous monitoring.

Source: Skin Health and Disease

DOI: 10.1093/skinhd/vzaf050

Authors: Bahareh Abtahi-Naeini, Maryam Derakhshan, Ali Emamjomeh, Azam Ghehsareh Ardestani, Somayeh-Sadat Momenzadeh, Mahsa Pourmahdi-Boroujeni

Institution: Isfahan University of Medical Sciences

Language: English

Topic: Histiocytic Disorders and Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,597