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Retrograde and Contralateral Metastasis of Clear Cell Renal Cell Carcinoma to the Spermatic Cord: A Case Report

Year: 2025

Type: article

Abstract: Clear cell renal cell carcinoma (ccRCC) is known to display synchronous and metachronous metastases to a diverse set of organs. Retrograde and contralateral metastases of ccRCC are rare, with few cases in the literature. The mechanism of spread in these cases is thought to be facilitated by either the direct extension of tumor into the renal and gonadal veins or by the vertebral venous plexus. Here, we present a rare case of contralateral and retrograde ccRCC metastasis with extensive venous involvement.

Source: Cureus

DOI: 10.7759/cureus.90970

Authors: Joy M Hoang, Munira Charania, Marcus L Quek, Maria M Picken

Institutions: Loyola University Medical Center, Loyola Medicine

Language: English

Topic: Renal cell carcinoma treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4413559915