Work

Cobalt‐Catalyzed Green Alkylations of Anilines with Tetrahydrofurans

Year: 2025
Type: article
Abstract: The use of bio-renewable resources as starting materials and reagents in synthetic chemistry is an important area for sustainable development. The use of tetrahydrofuran (THF) and 2-methyltetrahydrofuran (2-MeTHF) is reported, which can be obtained from lignocellulosic biomass, as potential alkylating agents for anilines. The developed N-alkylation process is catalyzed by the readily available cobalt salts and employs industrially available syngas as a reducing agent. The reported approach allows for the green and cost-effective production of N-alkylanilines from readily available feedstocks.
Source: ChemSusChem
Language: English
Open Access status: hybrid
Estimated APC paid: $4,550
OpenAlex ID: W4413576266
FWCI:
Cites: 45
Cited by:
Related to: 10