Year: 2025
Type: article
Study design: Observational Study
Abstract: Objective: To determine the prevalence of celiac disease in adult patients with iron deficiency anemia and identify any potential clinical and laboratory markers associated with the condition. Methods: This cross-sectional observational study was conducted at Gulab Devi Hospital, Medicine Department, IPD (Indoor Patient Department) during September 2024 to march 2025. Data were collected from 160 patients including demographic information (age, gender, etc.), clinical symptoms, laboratory results, and the outcome of the serological tests for celiac disease. Results: Data were collected from 160 patients, with a mean age of 42.3 ± 15.8 years. Among the participants, 46.9% were male and 53.1% were female. The most common symptoms reported were fatigue (84.4%), pallor (75%), and weakness (68.8%). Abdominal discomfort, weight loss, and bloating were less frequent, occurring in 28.1%, 18.8%, and 21.9% of patients, respectively. Laboratory results showed a mean hemoglobin level of 9.2 ± 1.4 g/dL, serum ferritin of 9.4 ± 3.6 ng/mL, and transferrin saturation of 10.2% ± 4.7%, indicating severe iron deficiency. Conclusion: It is concluded that celiac disease is a significant but underdiagnosed cause of iron deficiency anemia in adults, with a prevalence of 7.5% in the studied cohort. Clinicians should consider screening for celiac disease in patients with unexplained IDA, particularly those who do not respond to iron supplementation.
Authors: Shaheen Bano, Abdul Rehman Pasha, Fatima Javad, Hafiz Abdul Rauf, Fahad Aman Khan, Nazish Shafi
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4413584246