Work

Synthesis of Poly‐Substituted Imidazo[1,2‐ a ]Pyridines via a Double Annulation Strategy

Year: 2025

Type: article

Abstract: A highly efficient domino process consisting of conjugate substitution, nucleophilic addition, and cycloisomerization from the reaction of enaminonitrile with propargylamine allowed for a successive double ring closure to afford a densely functionalized imidazo[1,2‐ a ]pyridine through formation of three C─N bonds.

Source: Asian Journal of Organic Chemistry

DOI: 10.1002/ajoc.70175

Authors: Myungho Jung, Sunhee Lee, Dohui Ku, Dageum Kang, Ikyon Kim

Institution: Yonsei University

Language: English

Topic: Synthesis of heterocyclic compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,030

Funder: National Research Foundation of Korea