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Optimization of Novel Quinazolines as Potent Aurora Kinase Inhibitors for Triple-Negative Breast Cancer Treatment

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Year: 2025
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c00107
Authors: Liang Long, Bin Zhang, Wei Peng, Yujia Pan, Hongjin Zhai, Bao Cheng, Zhengchao Tu, Zijie Long, Huihao Zhou, Quentin Liu, Gui Lu
Institutions: Guangzhou University of Chinese Medicine, Sun Yat-sen University, Dalian Medical University, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Jinan University, Jinan University, Third Affiliated Hospital of Sun Yat-sen University
Language: English

Topic: Synthesis and biological activity
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Guangdong Provincial Key Laboratory of Construction Foundation, Basic and Applied Basic Research Foundation of Guangdong Province
Awards: G2152750272, G2410909804, G3463892342
OpenAlex ID: W4413633226
FWCI: 0.881
Cites: 36
Cited by: 3
Related to: 10
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