Work

Dynamic changes of pulmonary function and immune function in children with mycoplasma pneumonia of different severity and their predictive value for disease prognosis: a retrospective cohort study

Year: 2025

Type: article

Abstract: Purpose: To explore the dynamic changes in pulmonary and immune function among children with Mycoplasma pneumoniae pneumonia (MPP) and evaluate their value in disease severity stratification and prognosis prediction. Method: A retrospective cohort of 225 pediatric patients with varying degrees of MPP severity and disease course was analyzed. Lung function and immunological indices were measured and compared across groups. Results: Children with MPP exhibited significant impairments in pulmonary function and alterations in immune profiles compared to controls. These changes were associated with both disease severity and recovery status. Conclusion: Pulmonary and immune function markers may serve as useful indicators for assessing severity and recovery in pediatric MPP. Their clinical application could improve individualized management strategies.

Source: Frontiers in Medicine

DOI: 10.3389/fmed.2025.1624256

Authors: Zheng Liu, Wen Deng, Wenlin Xu, Linlin Ye, Zhihui Rao

Institutions: Children's Hospital of Chongqing Medical University, Chongqing Medical University, Jiangxi Provincial Children's Hospital

Language: English

Topic: Pneumonia and Respiratory Infections

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801