Work

Single-Cell and Plasma Proteomics Do Not Differentiate Patients With and Without SARS-CoV-2 Antigenemia in Convalescence in a Cohort of 100 Patients

Year: 2025

Type: article

Study design: Observational Study

Abstract: Plasma samples obtained approximately 3 (n = 100) and 12 months (n = 78) after acute SARS-CoV-2 infection were tested for S1, spike, and N antigens. There were no significant differences in plasma proteins or single-cell protein expression levels on immune cells between those with and without plasma antigen detected.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofaf515

Authors: Shaun Pienkos, Zoe Swank, Rebecca E Hamlin, Mallika Rao, Phillip Grant, Hector Bonilla, Karen Jacobson, Prasanna Jagannathan, Upinder Singh, David R Walt, Aruna Subramanian, Catherine Blish

Institutions: Stanford Medicine, Stanford University, Brigham and Women's Hospital, Harvard University, Wyss Institute for Biologically Inspired Engineering, University of Iowa, Chan Zuckerberg Biohub San Francisco

Language: English

Topic: SARS-CoV-2 and COVID-19 Research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053

Funders: National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases

Awards: G1162563573, Stanford Training Program in Lung Biology

OpenAlex ID: W4413637298

FWCI: 0.709

Cites: 11

Cited by: 1

Related to: 10