Discovery of Gut-Restricted PRMT5 Inhibitors to Intercept Colorectal Cancer in Patients with Genetic Loss of Tumor Suppressor Adenomatous Polyposis Coli
Year: 2025
Type: article
Source: Journal of Medicinal Chemistry
Authors: Fabian Hulpia, Wim Schepens, Susan Lepri, Johan Nicolaï, Zhengyu Jiang, Sylvia F. Boj, Tammy L. Bush, Mary-ambre Carvalho, Falian Chen, Gerald Chu, Kathleen W. Clancy, Zienab Etwebi, Melissa Everaerts, Yi Fan, Froylan Omar Fernandez Candelaria, Albi Francis, Mark S. Hixon, Ferran Jardi, Shuai Jin, Egor M. Larin, Stefaan Last, Joseph E. Leenaerts, Siyu Li, Alexandra G. Liddane, Ferdinand H. Lutter, Dan Lv, Bethany Mattson, Cynthia M. Milligan, Aaron N. Patrick, Gauri Anand Patwardhan, Laura Perez-Benito, Serge Pieters, Evelien Renders, Ed Retzbach, Constance Smith-Monroy, José Silva, Mariana Silva, Hans Sterckx, Gerben ten Hag, Claudia Thäte, Sven Van Brandt, Carla S. Verissimo, Guido Verniest, Eileen Vesely, Irene Vetrano, Petra Vinken, Yufei Wang, Victoria Wong, Xuemei Yao, Jie Yang, Remco Zijlmans, Kurtis E. Bachman, David Pocalyko, Juan-Miguel Jimenez, Dana Gaffney, Jan Willem Thuring
Institutions: Johnson & Johnson (United States), Pharmaron (China)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: closed
OpenAlex ID: W4413637783