Work

Predictive value of contrast-enhanced ultrasound in assessing the risk of recurrent in ipsilateral anterior circulation ischemic stroke

Year: 2025

Type: article

Abstract: PURPOSE: To evaluate the value of conventional ultrasound and contrast-enhanced ultrasound (CEUS) in predicting the risk of recurrence in patients with ipsilateral anterior circulation ischemic stroke (ACIS). METHODS: The clinical, laboratory, and ultrasound data of 295 patients who were hospitalized for their initial ACIS between January 2016 and May 2023 were collected. Based on 6–24 months follow-up results, patients were categorized into two groups: the recurrence group and the non-recurrence group. Differences in clinical characteristics, laboratory tests, and ultrasound findings between the two groups were analyzed. RESULTS: Statistically significant differences were observed between the recurrence and non-recurrence groups in terms of age, carotid plaque side, and CEUS grade (P < 0.05). Multivariate analysis identified CEUS grade as an independent risk factor for ACIS recurrence(P = 0.032). A CEUS grade ≥ 2 demonstrated high predictive accuracy for recurrence, with a sensitivity of 91.04%, specificity of 85.09%, and overall accuracy of 86.44%. CONCLUSION: CEUS grade could independently predict the recurrence risk of ipsilateral ACIS, providing valuable insights for the clinical management and prevention of recurrent ipsilateral ACIS in this patient population.

Source: BMC Medical Imaging

DOI: 10.1186/s12880-025-01887-8

Authors: Jinyong Zhan, Zhifei Ben, Jue Wang, Kaiying Xu

Institution: Ningbo No. 2 Hospital

Language: English

Topic: Cerebrovascular and Carotid Artery Diseases

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,090